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Learn · Hormones

Insulin: The Aging Accelerator

1-minute read 25 XP in app 6 cards

Insulin is the master switch

Chronically elevated insulin drives fat storage, inflammation, and activates mTOR — the growth pathway that accelerates aging. Insulin sensitivity may be the single best longevity biomarker.

#1 modifiable longevity biomarker

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What spikes insulin?

Swipe left for LOW insulin impact, right for HIGH.

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Fact

HOMA-IR — the test you should ask for

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) uses fasting glucose × fasting insulin ÷ 405. Below 1.0 = insulin sensitive. 1.0–2.0 = average. Above 2.0 = resistance brewing. The test is cheap and most labs run it; HbA1c misses early resistance because glucose looks fine while insulin's working overtime.

<1.0 HOMA-IR target for insulin sensitivity

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The post-meal walk

Tap to see what 10 minutes of walking after a meal actually does.

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Time-restricted eating impact

Stages of how a 14:10 eating window affects insulin sensitivity.

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Takeaway

Key Takeaway

Keep insulin low and sensitivity high: eat whole foods, walk after meals, practice time-restricted eating, and build muscle.

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