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Your Gut & Inflammation

1-minute read 25 XP in app 6 cards

Inflammation starts in the gut

70% of your immune system lives in your gut. When the gut barrier weakens ('leaky gut'), bacterial toxins leak into your bloodstream, triggering whole-body inflammation.

70% of immune cells are in the gut
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Explore the gut-inflammation axis

Tap each factor to learn how it impacts gut health.

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Fact

The fiber gap

The average adult eats 15g of fiber daily. Optimal is 30-40g. Every 10g increase reduces all-cause mortality by 10%.

30-40g optimal daily fiber
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Estimate the gap

How many grams of fiber does the average adult eat daily?

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Fact

Short-chain fatty acids — the gut's longevity payout

When gut bacteria ferment fiber, they produce short-chain fatty acids (SCFAs) — mainly butyrate, propionate, acetate. Butyrate is the colon's preferred fuel and the strongest endogenous anti-inflammatory signal we have: it tightens the gut barrier, dampens NF-κB inflammation, and signals to the brain via the vagus nerve. Diverse fiber sources (resistant starch, legumes, onions, oats, berries) drive higher SCFA production than a single fiber supplement.

SCFAs butyrate / propionate / acetate
Takeaway

Key Takeaway

A healthy gut is your #1 defense against chronic inflammation. Eat 30+ grams of fiber daily from diverse plant sources, and lean toward fermentable fibers (legumes, oats, onions, resistant starch) so your gut bacteria can produce butyrate + the other SCFAs that lower inflammation.

References

  1. SCFAs and the gut-immune axisParada Venegas et al., 2020

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