Reading on the web. Open in the Thier app for the full interactive version, progress tracking, and XP.
Open
GLP-1 Quiz
Quiz
On which organ does GLP-1 NOT act directly?
Pick the outlier.
GLP-1 acts on pancreas (insulin release), stomach (slowed emptying), and brain (satiety). The thyroid is not a direct target — though there's a boxed warning for thyroid C-cell tumours based on rodent studies, the clinical human signal remains small.
Quiz
Roughly how much lean mass is lost on GLP-1 weight loss?
As a percentage of total weight lost.
~40% of weight lost is lean mass. Similar to diet-only weight loss but still meaningful — which is why resistance training and adequate protein matter on these drugs.
Quiz
What happens to most of the weight lost if you stop a GLP-1?
Long-term data from STEP 4.
STEP 4 showed roughly two-thirds of lost weight comes back within a year of stopping, without lifestyle intervention. These are chronic-use therapies, not a cycle-and-done intervention.
Track your progress
Read the cards above, then mark this lesson complete to track your progress.
Reading without an account? Sign in to save progress across devices.