Rapamycin & Metformin
The most promising longevity drugs
Two existing drugs — rapamycin and metformin — have shown remarkable anti-aging effects in studies. Both are already FDA-approved for other conditions.
Rapamycin: the mTOR inhibitor
Discovered in Easter Island soil, rapamycin inhibits mTOR — the growth pathway that accelerates aging when chronically active. It extends lifespan in every organism tested.
Rapamycin's journey
Trace the remarkable history of rapamycin.
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Rapamycin vs Metformin
Compare these two longevity drug candidates.
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True or False
Metformin is only useful for people with diabetes.
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What does rapamycin do?
Select every confirmed biological effect.
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The TAME trial
TAME (Targeting Aging with Metformin) is the first FDA-approved clinical trial to test a drug specifically for aging. If successful, it could change how we regulate anti-aging medicine.
Key Takeaway
Rapamycin and metformin are the most promising longevity drugs in clinical research. Both target fundamental aging pathways, but self-medicating is risky — wait for trial results.