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NAD+ & Sirtuins
The fuel of cellular repair
NAD+ (nicotinamide adenine dinucleotide) is a coenzyme in every cell. It powers DNA repair, energy production, and anti-aging sirtuins — but levels drop 50% by middle age.
50%
NAD+ decline by age 50
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NAD+ decline over time
See how NAD+ levels change across your lifetime.
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Fact
Sirtuins: the longevity genes
Sirtuins (SIRT1-7) are enzymes that protect against aging by repairing DNA, silencing inflammatory genes, and boosting mitochondria. They require NAD+ as fuel to function.
7
sirtuin genes in humans
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Match the sirtuin
Match each sirtuin to its primary function.
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NMN vs NR: supplement comparison
Compare the two main NAD+ precursor supplements.
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Myth or Fact?
Swipe left for FACT, right for MYTH.
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Takeaway
Key Takeaway
NAD+ is the master fuel for cellular repair. Exercise, fasting, and precursor supplements (NMN/NR) may help maintain levels, but human longevity data is still emerging.
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